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Metastatic follicular dendritic cell sarcoma of the stomach : A case report and review of the literature

Journal Volume 67 - 2004
Issue Fasc.2 - Case reports
Author(s) A. Geerts, E. Lagae, K. Dhaene, M. Peeters, A. Waeytens, P. Demetter, C. Cuvelier, L. Defreyne, M. De Vos, P. Pattyn
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(1) Department of Gastroenterology ; (2) Department of Surgery ; (3) Department of Pathology ; (4) Department of Radiology, University Hospital Ghent, Ghent.

Follicular dendritic cell (FDC) sarcomas are rare tumours, typ- ically seen in lymph nodes. However, in about one third of the reported cases, a FDC sarcoma presents as an extranodal mass. Involvement of the gastrointestinal tract is extremely rare, and only 3 cases have been described to date. We report on a 40-year-old female patient with a follicular den- dritic cell sarcoma located in the stomach and the presence of a metastasis in the liver at the time of diagnosis. Severe asthenia, nausea, back pain and loss of weight were the presenting symp- toms. A CT scan of the abdomen and an upper gastrointestinal endoscopy revealed a tumour mass in the stomach. The diagnosis of a FDC sarcoma was made on histological and immunohistochemical findings. We report the second case of a FDC sarcoma presenting in the stomach. Due to its rarity, a FDC sarcoma seldom enters the differential diagnosis of spindle cells neoplasms of the gastrointestinal tract. Complete surgical resection is the treatment of choice for FDC sarcoma. (Acta gastroenterol. belg., 2004, 67, 223-227).

© Acta Gastro-Enterologica Belgica.